Teewinot Life Sciences’ Patented Biosynthetic Tech Cuts Costs and Produces Clinical-Grade Cannabinoids

Company’s IP portfolio, including proprietary technology and biosynthetic methods, features seven U.S. patents and patent filings in numerous other key countries around the world
Eliminating the high costs of cultivating plants, Teewinot Life Sciences Corporation delivers pure, consistent pharmaceutical-grade cannabinoids
Company’s goal is to cut costs and approach cannabinoid production like a pharmaceutical company, not as a cannabis firm

Teewinot Life Sciences Corporation has an advantage in consistently producing pure, clinical-grade cannabinoids with its patented biosynthetic technology. The results eliminate the watering and electrical costs of traditional plant cultivation, as well as the variances in quality. Instead, its method offers low-cost cannabinoids in a pure, consistent clinical grade.

Teewinot Life Sciences is a Tampa, Florida-based global biopharmaceutical company focused on cannabinoid clinical development utilizing patented and proprietary synthetic biology and biocatalysis technology. Its strategy involves the production and use of cannabinoid molecules. The goal of the company is to produce, at lower cost, consistent and pure cannabinoids that it believes can be used to develop superior human therapies.

The company and its wholly-owned subsidiaries have patented technologies that produce individual cannabinoids at commercial scale for a wide variety of markets. It approaches the process as a straight medical company, not as a marijuana firm. Its process involves the pharmaceutical manufacture of cannabinoids through biocatalysis and synthetic biology.

Cannabinoid biosynthetic enzymes are produced in microorganisms transformed with cannabinoid biosynthetic genes. Those enzymes are then used to manufacture pharmaceutically-pure cannabinoids.

The goal is to improve human therapies. The company has now secured seven U.S. patents and has a portfolio of patent applications in a number of countries. Teewinot Life Sciences has subsidiaries in Ireland and Canada.

For more information, visit the company’s website at www.TLSCorp.com

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ChineseInvestors.com, Inc. (CIIX) Offering Innovative Access to Cryptocurrency

Despite China’s ban on cryptocurrency, CIIX is positioned to lead the way in cryptocurrency education and awareness for the Chinese-speaking community
Demand for bitcoin continues to rise despite China’s ban on cryptocurrency
Company is committed to the education and growth of cryptocurrency and providing innovative ways of making bitcoin more accessible

ChineseInvestors.com, Inc. (OTCQB: CIIX) is continuing its commitment to cryptocurrency education and awareness for the Chinese-speaking community. Its educational services seek to answer the average person’s curiosity while simultaneously providing skilled investors with up-to-date news on digital currency. Using the Chinese language character sets, CIIX provides analysis and education that is accessible to the Chinese-speaking community worldwide. CIIX provides information on how to purchase bitcoin, real-time market commentary and consulting services, as well as advertising and public relations services.

Cryptocurrency is appealing in that it allows investors to diversify their portfolios. This shift away from traditional investment opportunities brings with it an air of excitement. Bitcoin is being exchanged by investors in unregulated offline platforms in an effort to bypass China’s ban (http://cnw.fm/D3Hxq). The scarcity of bitcoin, and the complexity of mining new coins, is part of the draw. Despite a recent post by China’s Communist Party paper bashing bitcoin and insisting that cryptocurrency is a load of hype, demand has continued to rise (http://cnw.fm/jA6Le).

CIIX is committed to raising awareness and education surrounding bitcoin. The company now hosts a daily broadcast from the NYSE, titled ‘Bitcoin MultiMillionaire’, with the intent of educating Chinese-speaking viewers on the most current news in cryptocurrency. In addition, CIIX is committed to bitcoin growth and has installed a bitcoin ATM in the lobby of its headquarters in San Gabriel, California. The Chinese middle and upper class is growing and looking for new ways to diversify their portfolios. ChineseInvestors.com is ready and able to offer them innovative accessibility to cryptocurrency.

For more information, visit the company’s website at www.ChineseInvestors.com

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Skinvisible, Inc. (SKVI), Quoin Pharmaceuticals Proposed Merger to Address Opioid Pain Management Market

A merger between Skinvisible and Quoin will enable a successful entry on the post-surgical pain management market
Opioids – which typically refer to oxycodone, hydrocodone, and fentanyl – are highly addictive painkillers; nearly three in 10 Americans prescribed opioids for chronic pain will abuse them
Opioids are becoming increasingly deadly to Americans; in 2016, two-thirds of drug-related deaths involved opioids; in fact, since 1999, opioid-related deaths in the United States have increased nearly fourfold
Drug abuse is a burden shared by every state; nearly 63,600 Americans lost their lives to drug overdoses in 2016 – a 21 percent increase over the previous year; from 2000 to 2016, the U.S. Centers for Disease Control and Prevention estimates that more than 600,000 people died from drug overdoses in the United States
Every 25 minutes, a baby in the United States is born suffering from opioid withdrawal

Skinvisible, Inc. (OTCQB: SKVI) previously announced the signing of a Letter of Intent for a proposed merger with Quoin Pharmaceuticals Limited – a partnership that could address significant unmet medical needs on the pain management market. If both parties agree on the terms, the merger should be completed this year, and the resulting entity will operate under the name Quoin Pharmaceuticals Inc. and will continue to trade on the OTCQB market.

Quoin’s strength is within the area of pharmaceutical product development for products that address some of the most serious present-day health problems. Skinvisible is the developer of innovative delivery system technologies that can enhance product delivery and performance.

Quoin’s lead product is QRX001 – a transdermal NMDA receptor antagonist for the effective treatment of pain following surgery. QRX001 delivers up to 72 hours of effective pain relief after surgical interventions. Almost 30 clinical studies have been performed to date on the NMDA receptor antagonist, clearly showing that sub-anesthetic doses reduced 24-hour PCA morphine consumption; reduced post-operative nausea and vomiting; reduced pain intensity; resulted in adverse events that were mild or absent; and generated better results than any other single product or combination. The aim of the product is to also reduce the use of opioids for pain management following an operation.

Upon the product’s launch, QRX001 is expected to provide surgeons with a new and effective alternative to opioids. Opioid abuse has reached an epidemic level in the U.S., with opioid overdoses causing more than 90 deaths per day (http://cnw.fm/7vtpP). This number has grown exponentially in the past decade, according to the Centers for Disease Control and Prevention, with opioid use remaining widespread despite the risks. Today, approximately 12 million Americans report that they use pain killers in a non-medicinal way.

The opioid market in the U.S. is estimated at $6 billion annually. With the opioid epidemic now deemed a National Health Emergency, there is a significant push to find new products that reduce or eliminate their use, particularly in a post-surgical setting, which is where 50 percent of people who become addicted first become exposed to these drugs.

In addition to wrecking lives, opioid abuse poses a massive burden on the economy. Adding up money lost from costs related to health care, addiction treatment, reduced work productivity and crime, the Centers for Disease Control and Prevention estimates that the economic burden of the opioid crisis is more than $78.5 billion per year.

Almost half of the victims were first introduced to opioids after undergoing surgery. According to the National Center for Health Statistics, 100 million surgeries take place in the U.S. every year (http://cnw.fm/k4cxW). At least 50 million of these surgical interventions necessitate the use of post-operative pain management pharmaceuticals.

Currently, the pain management market in the U.S. is fueled by a number of sectors. The most prominent ones include post-operative pain relief, arthritis pain, cancer pain, migraine and neuropathic pain. As larger Western populations age and become susceptible to an array of medical conditions, the need for new pain management developments will grow even further. The partnership between Skinvisible and Quoin perfectly positions the two companies to address these growing unmet needs on the pain management market.

The Skinvisible announcement states that new technologies and product synergies between the two companies could potentially provide significant value to shareholders after the merger. Together, Skinvisible and Quoin could maximize their product development opportunities, as noted by Skinvisible President Terry Howlett. The official news release also included a disclaimer regarding ‘forward looking’ statements.

For more information, visit the company’s website at www.Skinvisible.com

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Regulation and Oversight of Virtual Currencies by SEC and CFTC Agencies to be Reviewed, Congressional Hearing Set

The Committee on Banking, Housing and Urban Affairs sets hearing for February 6 to review oversight role of the SEC and CFTC over virtual currencies, such as bitcoin
In an op-ed written jointly by the SEC and CFTC, agency chiefs say they would support policy efforts to revisit framework of their cryptocurrency regulation; both will testify before the committee
Agencies say they will seek to maintain integrity and transparency in the volatile cryptocurrency markets; goal is to protect all market participants and investors

Virtual currency oversight by the Securities and Exchange Commission (SEC) and the U.S. Commodity Futures Trading Commission (CFTC) will be reviewed after the heads of both agencies testify on February 6 before a hearing of the Committee on Banking, Housing and Urban Affairs (http://cnw.fm/Aqb3b).

Jay Clayton, chairman of the SEC, and J. Christopher Giancarlo, chairman of the CFTC, will testify at the hearing. What they will say was telegraphed in their recent jointly-authored op-ed (http://cnw.fm/sb3DN). In it, they noted that most check-cashing and money transmission services are state regulated. They argue that most of the internet-based cryptocurrency trading platforms have registered as payment services and, therefore, are not subject to direct regulation today by the two federal agencies.

Their op-ed said, “Many of the internet-based cryptocurrency trading platforms have registered as payment services and are not subject to direct oversight by the SEC or CFTC. We would support policy efforts to revisit these frameworks and ensure they are effective and efficient for the digital era.”

The agencies said they seek market integrity and transparency. In the op-ed, they note that they seek review of their oversight of these markets and would continue to work with law enforcement to enforce this goal. “The CFTC and SEC, along with other federal and state regulators and criminal authorities, will continue to work together to bring transparency and integrity to these markets and, importantly, to deter and prosecute fraud and abuse,” they added.

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Global Hemp Group, Inc. (CSE: GHG) (FRANKFURT: GHG) (OTC: GBHPF) is “One to Watch”

U.S. hemp retail market estimated at $1.8 billion by 2020 with 22% CAGR
Global hemp-based cannabidiol (CBD) segment projected to reach $3 billion by 2021
Disruptive potential for industrial hemp products offers substantial rewards

Global Hemp Group, Inc. (CSE: GHG) (FRANKFURT: GHG) (OTC: GBHPF), headquartered in British Columbia, Canada, is a publicly traded company founded in 2014. Global Hemp Group is focused on acquiring and developing a strategic portfolio of like-minded companies that believe in the significant potential of the industrial hemp plant. Global Hemp Group’s focused on attracting joint venture partners across all sectors of the industrial hemp industries with the commitment to improve quality of life by researching, developing and distributing sustainable materials, products and services produced from hemp.

The company’s mission is to build a strategic portfolio of hemp-based companies that operate synergistically to consistently deliver a solid ROI to its shareholders. Global Hemp Group has established the concept of Hemp Agro-Industrial Zone (HAIZ) (https://globalhempgroup.com/hempagro/) in order to build cooperative mechanisms across industrial sectors with a focus on different parts of the hemp plant. Under the HAIZ strategy, Global Hemp Group brings together capital, farmers and labor in an effort to build a “soil-to-shelf” portfolio of complimentary companies and joint venture partners in the global hemp industry.

Global Hemp Group has chosen to only work with suppliers of high quality, sustainable raw materials and finished products derived from the hemp plant. Among the leading industries utilizing industrial hemp’s exceptional properties is the automotive sector, building materials market, bio-composites, energy-related markets, super-foods, nutritional supplements, nutraceuticals and the cannabinoid markets. Guided by the principal theme of “global environmental stewardship,” Global Hemp Group focuses on the key concepts of sustainability and social responsibility in all its endeavors.

Global Hemp Group’s joint venture with publicly traded Marijuana Company of America on hemp cultivation trials in 2017, designed to develop commercial hemp production on the Acadian peninsula of New Brunswick, Canada, for the first time in 20 years, was a great success. The partners are preparing for the upcoming changes in Canada’s cannabis legislation that will permit cannabinoid extraction from industrial hemp. Farmers have already been recruited to plant a minimum of 125 acres of industrial hemp for the 2018 growing season, with the goal of increasing the acreage under cultivation to 1,000+ acres by year three of the joint project. Global Hemp Group is preparing an application for a processing license to extract cannabidiol (CBD) and other cannabinoids from the upcoming industrial hemp crop. Discussions are also underway with potential processing partners for the extraction of cannabinoids and straw processing for building materials for the upcoming harvest in October 2018, with a longer term plan to establish permanent processing facilities by October 2019.

Global Hemp Group is led by Charles Larsen as its president, CEO and chairman of the board. Larsen’s more than 30 years of experience working in government, public, private and startup companies as an executive manager includes being the founding president of Medical Marijuana, Inc., the first public company in the Cannabis space. Larsen is also a founder and current director of Marijuana Company of America, Inc., and has been actively involved in the cannabis and hemp industry for nearly a decade. Larsen is joined by Curt Huber, who serves as CFO and director. Huber is an independent corporate and financial consultant with more than 25 years of experience in all facets of public companies among many different sectors including mining, oil and gas, and technology.

Also joining the management team as director is Dr. Paul T. Perrault, an agricultural economist trained in cooperative development and in rural development. Perrault’s experience includes years of consulting on rural development projects introducing new crops in several developing countries and strengthening agricultural research organizations, principally in Africa. Jeff Kilpatrick also serves as a director and is currently a program supervisor of Alachua County Department of Court Services in Gainesville, Florida. Kilpatrick, who spent 21 years in the U.S. Coast Guard, is a member of LEAP – Law Enforcement Against Prohibition – and is president elect for the National Association of Pretrial Services Agencies (NAPSA).

Global Hemp Group’s business philosophy is “A healthier future through sustainable business strategies.”

For more information, visit the company’s website at www.GlobalHempGroup.com

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Riot Blockchain, Inc. (NASDAQ: RIOT) Investments Solidify Effort to Build Decentralized Tech Platforms

Company’s investments in Verady, Coinsquare and TessPay among recent work to increase security for transactions
Blockchain, cannabis sectors accounted for nearly 10 percent of rising daily activity for TD Ameritrade in 4Q2017
Estimated $10 billion in cryptocurrency transacted each day

Riot Blockchain, Inc. (NASDAQ: RIOT) is advancing its focus on the rising blockchain technology and its cryptocurrency applications, as exemplified by its November announcement of its strategic investment in Verady, LLC, a company that provides accounting, auditing and verification for blockchain-based assets such as cryptocurrencies (http://cnw.fm/lNMe5). The strategy paid off with news that Riot Blockchain’s stock surged from $7 in November to more than $46 in a month, and the company remains committed to gaining “exposure to the blockchain ecosystem through targeted investments in the sector.”

Riot’s primary focus is on the bitcoin and Ethereum cryptocurrencies, and the company owns a share in Coinsquare, a Canada-based cryptocurrency exchange, as well as a majority share in TessPay, which serves as a blockchain-enabled payment vehicle for wholesale telecom carriers. Despite fluctuations in the value of bitcoin as the stock reached stratospheric levels following a hard-charging yearlong rally, and amid ongoing concerns in some sectors that its value is being propped up (http://cnw.fm/4txgW), bitcoin’s price remains exponentially above the value of an ounce of gold, which it passed last March.

A NetworkNewsWire article about the popularity of blockchain and cannabis-related stocks cited TD Ameritrade in reporting that daily average trades for the last quarter of 2017 were up 49 percent from the previous year, with trades in the blockchain and cannabis sectors accounting for between six and nine percent of daily activity (http://cnw.fm/nrQr1). Verady’s website (www.Verady.com) notes that over $10 billion worth of cryptocurrency changes hands each day in transactions worldwide, with no framework for proper tracking, reconciliation or reporting. “Audit and Accounting Standards haven’t caught up,” it states, citing its mission to provide the auditing and accountability services for major cryptocurrency companies. In December, Verady announced a strategic partnership with Georgia-based accounting organization Acuity and launched its VeraNet platform as it worked on a convergence of cryptocurrency wallet data with traditional accounting tools for businesses (http://cnw.fm/y3Ubd).

John O’Rourke, chairman and CEO of Riot Blockchain, referred to the company’s acquisition of a stake in Verady as continuing its commitment to building blockchain technologies as a first mover on the NASDAQ focused on those technologies. Verady stated that it will use the investment to strengthen itself by advancing its technology and increasing the size of its team. On January 30, the company announced its appointment of cybersecurity expert and strategic executive Christopher Ensey as COO. As the former COO of Dunbar Security Solutions, Ensey managed over 150 security professionals across physical and digital operations while capturing over 100 mid to large enterprise clients (http://cnw.fm/7DBVb). On January 17, the company appointed experienced blockchain data mining manager Jeffrey Vormittag as the COO of its wholly owned subsidiary, Riot Blockchain Canada Inc.

The blockchain is a decentralized and encrypted ledger system established to ensure the security and verifiability of transaction records without the need for intermediaries, which came to include banks as the popularity of blockchain-based cryptocurrencies began to rise. Blockchain “miners” work under an international system set up to establish a “proof of work” verification protocol. Riot Blockchain perceived the potential of the technology early on and, in October, redesigned its brand as it began work to establish an advisory board that has sufficient technical experience to help it become a leading authority and supporter of blockchain.

For more information, visit the company’s website at www.RiotBlockchain.com

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Lexaria Bioscience Corp. (CSE: LXX) (OTCQX: LXRP) Enters Agreement with Cannabis-Infused Edibles Manufacturer

Lexaria enters agreement with Cannfections to develop an innovative range of cannabis-infused chocolates and gummies incorporating its proprietary technology, DehydraTECH™
Cannfection’s formulation and manufacturing expertise can be offered to other Lexaria licensee partners
The agreement is expected to generate new cannabis-based edible products for domestic and international markets

On January 25, 2018, Lexaria Bioscience Corp. (OTCQX: LXRP) (CSE: LXX) announced that it had entered into a seven-year agreement with Cannfections Group Inc. to provide its patented DehydraTECH™ technology for the development of a new range of cannabis-infused chocolates and gummies (http://cnw.fm/Hef3A). Cannfections is a new company, established by one of Canada’s leading chocolate manufacturers with over 85 years of experience in the production of high-quality chocolate and confectionery products for several prominent domestic and international chocolate brands. Cannfections is a pending entrant to the Licensed Producer program for cannabis-infused products.

Under this agreement, Lexaria is able to offer other licensee partners the use of Cannfections’ formulation and manufacturing expertise for the production of cannabis-infused chocolates and gummies, powered by Lexaria’s patented DehydraTECH™ delivery technology. This is expected to generate new product entries for Canadian cannabis edibles for the domestic market, as well as the growing number of international markets.

DehydraTECH™ is a patented, cost-effective and proven delivery technology that enhances the taste, smell, speed of action, bioabsorption and bioavailability of beneficial compounds in ingestible products. This technology has been awarded patents in the United States and Australia, and it has patents pending in 44 other countries. Lexaria is the only company in the world with a patent for the oral delivery of all non-psychoactive cannabinoids, such as cannabidiol (CBD). Lexaria’s patents involve the use of its proprietary technology for oral delivery of an extensive range of lipophilic active compounds, including cannabinoids, non-steroidal anti-inflammatory drugs (NSAIDs), vitamins and nicotine.

Lexaria’s proprietary DehydraTECH™ technology masks recognition of the flavor and odor of compounds by oral and olfactory receptors. It enables manufacturers to create healthier, low-sugar products by eliminating the sugars and sweeteners traditionally used in product formulations to mask bitter tastes and unpleasant smells. This technology also increases the bioabsorption of cannabinoids and other active ingredients by up to 10 times. While other delivery technologies typically take between 60 and 120 minutes to take effect, DeydraTECH™ has been proven to register the onset of effects within 15 to 20 minutes.

Consumers benefit significantly from the enhanced taste of edibles and the reduced time to effect. As a disruptor in the growing cannabis market, Lexaria’s technology can either reduce the cannabinoid per serving unit cost, or deliver stronger effects where serving levels are regulated. The company’s technology can be applied to the manufacture of diverse product dosage forms, including foods, emulsions, liquids, tablets and capsules. Lexaria has produced a range of products for testing, demonstration and sales. These include CBD tablets, protein energy bars, exotic teas and TurboCBD, a high-absorption hemp oil capsule containing ginseng and ginkgo.

Lexaria has signed several royalty agreements for the use of its proprietary delivery technology with companies in Canada and the United States. Its latest venture with Cannfections is another step in the company’s ongoing pursuit of strategic partnerships with leading global companies to expand adoption of its innovative technology and deliver increased value for shareholders.

For more information, visit the company’s website at www.LexariaEnergy.com

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Sunniva, Inc. (CSE: SNN) Begins Trading on the Canadian Stock Exchange

SNN is a vertically integrated medial cannabis company operating in California and Canada
Company’s goal is to increase shareholder value by boosting stock liquidity and increasing exposure to investors
SNN has a number of subsidiaries, including Sunniva Medical, Inc., CP Logistics, LLC, Natural Health Services Ltd., and Full Scale Distributors, LLC

Sunniva, Inc., (CSE: SNN) began trading on the Canadian Stock Exchange under the ticker symbol “SNN” in early January, it announced (http://cnw.fm/hT2WM). The company is a North American provider of medical cannabis products and services.

SNN is a vertically integrated medical cannabis company operating in California and Canada, both large medical cannabis markets. It is committed to the cultivation, production and distribution of low-cost products that are free from pesticides and other contaminants. Management of the company has a proven track record in health care and the biotech space.

“Listing on the CSE is an important milestone for Sunniva and a key piece of the equation in our plan to enhance shareholder value by increasing stock liquidity and exposure to investors,” Dr. Anthony Holler, founder and CEO of the company, stated in a news release. He added that the listing greatly expands the company’s pool of potential investors and offers a number of other benefits.

Leith Pedersen, president and co-founder of Sunniva, Inc., told Business of Cannabis in an interview that the company was starting construction on a state-of-the-art greenhouse growing facility in Cathedral City, California (http://cnw.fm/b0u4N). It is also planning a 700,000 sq. ft. facility in Oliver, B.C., he said.

Pedersen added that SNN’s wholly-owned subsidiary, Natural Health Services (NHS), is Canada’s largest referral network of medical cannabis patients to licensed producers in the country. It also operates eight clinics throughout western Canada and Ontario with greater than 76,000 patients, he said.

For more information, visit the company’s website at www.Sunniva.com

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Pivot Pharmaceuticals Inc. (PVOTF) is “One to Watch”

Transdermal cannabis-based therapy promises greater absorption, less side effects
Global medical marijuana market projected to reach $55.8 billion U.S. by 2025
Novel CBD delivery method targets array of unmet healthcare needs

Pivot Pharmaceuticals Inc. (OTCQB: PVOTF), based in Vancouver, Canada, is an emerging biopharmaceutical company engaged in the development and commercialization of pharmaceuticals and nutraceuticals that provide novel treatments for unmet healthcare needs. Pivot’s recent acquisition of BiPhasix ™ Transdermal Drug Delivery technology for the delivery of cannabinoids (CBD) to patients provides the answer for an age-old problem associated with cannabinoid-based therapies: the lack of a robust smoke-less delivery mechanism.

Research into the bioavailability of cannabinoid-based therapeutics shows that rates of absorption vary greatly between smoking cannabis to an orally-consumed product, with a difference noted even between individuals. Cannabinoids are degraded in the stomach and smoking may not appeal to patients for health or lifestyle reasons. Topical delivery, while a better alternative, has suffered from weak formulation issues. Transdermal cannabinoid delivery, on the other hand, could provide a better alternative route since it reduces side effects and bypasses other absorption issues. In addition, transdermal delivery provides the benefit of enabling patients to access a steady stream of medication over a prolonged period with fewer side effects.

Pivot Pharmaceutical’s newly created subsidiary, Pivot Green Stream Health Solutions Inc. (“Pivot Green Stream”), will focus on improving the bioavailability of cannabinoid-based and pharmaceuticals. BiPhasix™ has been tested in FDA and EMA approved human clinical trials, which have shown the delivery system enhances the bioavailability of many drugs and improves clinical outcomes. Pivot Green Stream is tasked with developing several natural health products containing cannabinoids (CBD) that can receive a Health Canada Natural Health Product (NHP) designation. This marketing method ensures a shorter development cycle and faster revenue generation opportunities.

Pivot Pharmaceuticals Inc., which has positioned itself as a growing and crucial vertical in the cannabis industry, represents a compelling opportunity in the biotechnology field. The company’s plans include working with Licensed Producers (LP) and Licensed Dealers (LD) to bring newer therapies to patients. The company has also applied to list on the Canadian Stock Exchange (CSE).

The global medical marijuana market is expected to reach a value of $55.8 billion by 2025, according to a new report by Grand View Research, Inc. The growing number of states and countries gaining approval for using cannabis in therapeutic applications is expected to continue driving the market forward.

Pivot Pharmaceuticals has assembled a highly experienced management team, bringing together a wealth of clinical, commercial, product development and financial experience. Among the many healthcare targets in Pivot’s pipeline are cancer supportive care, pain and inflammation, women’s sexual dysfunction, dermatology and eye disease.

For more information, visit the company’s website at www.PivotPharma.com

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PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Teams with UniQuest to Develop Novel Cannabinoid Delivery System

Global nasal drug delivery technology market expected to reach $64 billion by 2021
Development of CBD-infused soluble gel for nasal delivery targets range of diseases
Clinical benefits of Sol-gel delivery method include a safer, more reliable delivery platform with higher efficacy

Health sciences company PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) and UniQuest Pty Limited, the main commercialization company of the University of Queensland (UQ), Australia, are expecting 2018 to be an exciting, productive year for joint medical research projects. PreveCeutical Medical, headquartered in Vancouver, British Columbia, has entered into a research and option agreement with the University and UniQuest to develop a soluble gel to deliver cannabinoids directly to the brain via the nasal cavity. In a press release discussing the latest research project, UniQuest CEO Dr. Dean Moss said that PreveCeutical’s interest in the University’s intellectual property and expertise to develop soluble gels (Sol-gels) to deliver cannabinoids to the central nervous system (CNS) fit naturally with the company’s research goals (http://cnw.fm/zIB24).

“Sol-gels potentially provide a safer, more reliable platform to deliver drugs, such as cannabinoids, directly to the CNS, avoiding unwanted rapid metabolism, thus providing clinical benefit from direct nose-to-brain delivery,” Dr. Moss said in the release.

The global nasal drug delivery technology market is projected to reach $64 billion by 2021, expanding at a compound annual growth rate of 6.5 percent, according to a report issued by MarketsandMarkets (http://cnw.fm/x9T1Q). While the report is segmented based on dosage form, therapeutic application, end user, system, container and region, it also states “intranasal drug delivery is one of the most preferred drug delivery routes among patients as well as healthcare providers.”

PreveCeutical’s proprietary nasal formulations will be designed as a CBD-based nose-to-brain delivery system targeting a range of indications such as pain, inflammation, seizures and neurological disorders. Dr. Harry Parekh, chief research officer for PreveCeutical, will lead the Sol-gel cannabinoid project from his base at the University’s School of Pharmacy.

The Sol-gels begin as a liquid that is sprayed into the nose, which then forms a gel as it is warmed in the nasal cavity. This effectively bypasses the stomach and intestines – eliminating first pass metabolism – and may dramatically improve bioavailability, even compared to nasal sprays and other newer delivery systems.

“This feature can potentially be exploited to deliver drugs through the nasal mucosa,” Dr. Parekh said. “The longer-term goal is to develop Sol-gels as safe, reliable delivery systems for cannabinoid extracts across a range of disease indications.”

Terms of the research program, which has a target start date of March 1, 2018, state that PreveCeutical will own all intellectual property developed under the program and will be granted an option to negotiate an exclusive worldwide license to UniQuest’s background IP.

“Increasing evidence of the clinical benefits associated with cannabinoids and the recent legalization of medical marijuana across a number of jurisdictions were the drivers for the collaboration,” Stephen Van Deventer, PreveCeutical chairman and CEO, added in a news release. “Working with UniQuest and UQ will provide the company with unique opportunities to develop new health and wellness products… Nasal delivery of cannabinoids could potentially provide a safer and more reliable delivery platform with clinical benefits for pain, inflammation, seizures, and mental illness.”

For more information, visit the company’s website at www.PreveCeutical.com

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