• Lexaria held its virtual 2023 Annual Shareholders meeting on May 9, 2023
• On the agenda were the election of six director nominees, the ratification of the appointment of the company’s independent registered public accounting firm, and the approval of a one-time repricing of specific issued stock options, among others
• All items presented received approval, with the highest approval percentage standing at 97.6% and the lowest at 63.1%
• The meeting presented an opportunity for Lexaria to evaluate areas of expertise that would provide additional benefits to the company and its shareholders while also adding diversity to its board

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, on May 9 held its 2023 Annual Shareholder Meeting, in which 3,372,024 shares, constituting 56.3% of the company’s issued share capital, were represented.

Carrying on with the theme of the previous year’s Annual Meeting, the virtual 2023 Annual Shareholder Meeting adhered to COVID-19 protocols, with provisions for shareholders to vote via proxy. Among the meeting’s agenda items included the election of Chris Bunka, John Docherty, Nicholas Baxter, Ted McKechnie, Albert Reese Jr., and Dr. Catherine Turkel as directors. Shareholders also voted on the appointment of Malone Bailey LLP as auditors, the approval of the stock option pricing, and the approval of the amendment to the maxim number of shares issuable according to the incentive Equity Plan (https://cnw.fm/T5kov).

All items put to the vote were selected in favor of, with the highest approval percentage standing at 97.6% for the election of Dr. Catherine Turkel as director and the lowest standing at 63.1% for the approval of the addition of an evergreen formula to the Incentive Equity Plan. Percentages were calculated based on abstained votes being counted as a vote against the resolution.

Lexaria and its management expressed their support of recent initiatives the SEC and the Nasdaq Group took to encourage diversity within the board of directors of reporting companies. With the company reviewing its board composition annually, this meeting presented an opportunity to not only evaluate areas of expertise that would provide additional benefits to the company and its shareholders but also add to the diversity of its board. Lexaria hopes that with these appointments, it will further pursue its goal of leveraging technology in pharmaceutical applications. More so, it looks to make its patented DehydraTECH(TM) technology and offerings even more accessible to the masses (https://cnw.fm/LbIuk).

For more details, please visit Lexaria’s proxy statement filed with the Securities Exchange Commission via Edgar and with the BC Securities Commission and Ontario Securities Commission via SEDAR on March 22, 2023.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

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• Lexaria recently completed its 2,106,000-unit public offering at $0.95 per share – representing proceeds totaling over $2 million gross in support of the company’s growth
• Maxim Group LLC is acting as the sole placement agent in connection with Lexaria’s offering
• Earlier the company was granted four new patents, bringing its total to 32 granted and many more pending worldwide for its patented DehydraTECH(TM) technology
• Lexaria is currently seeking IND status from the FDA for use of DehydraTECH-processed CBD with hypertension and expects to begin dosing a new human clinical trial in October 2023

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, recently announced the closing of its 2,106,000-unit public offering. Each unit consists of one share of common stock, and one warrant to purchase one share of common stock. The common shares and accompanying warrants can only be purchased together in this offering but will be issued by the company separately and will be separable upon issuance.

Each unit in Lexaria’s public offering is being sold at $0.95 and will be immediately exercisable at $0.95 per share and expire five years from the date of issuance. Maxim Group LLC is acting as the sole placement agent in connection with Lexaria’s offering. Before deducting the placement agent fees and other offering expenses, gross proceeds totaled approximately $2 million (https://cnw.fm/rpRsN).

Lexaria’s patented DehydraTECH(TM) technology is designed to deliver lipophilic (fat-soluble) drugs and active pharmaceutical ingredients (“APIs”) more effectively. The major benefits of DehydraTECH-enabled drugs or consumer products include:

• Speeds up delivery – the subject feels the effects of the product in just minutes
• Increases bioavailability – the technology is much more effective at delivering the drug or product into the bloodstream
• Increases brain absorption – animal testing suggests significant improvement in the quantity of the drug delivered across the blood-brain barrier
• Improves drug potency – more of the ingested product is made available to the body, so lower doses are required to achieve the desired effect
• Reduces drug administration costs – lower doses mean lower overall drug costs
• Masks unwanted taste – the technology eliminates or reduces the need for sweeteners

Lexaria has demonstrated through animal studies a propensity for DehydraTECH to elevate the quantity of the drug delivered across the blood-brain barrier by as much as 1,700 percent, initiating additional new patent applications and opening possibilities for improved drug delivery. Since 2016, DehydraTECH has repeatedly demonstrated, through cannabinoids and nicotine, the ability to increase bio-absorption by up to five to ten times, reduce the onset time from one to two hours to just minutes, and mask unwanted tastes.

Lexaria is exploring additional orally administered bioactive molecules, including antivirals, cannabinoids, PDE5 inhibitors, oral nicotine and more.

The company currently has 32 granted patents, with several more pending worldwide – after recently being granted four new patents in Japan, Australia, Canada, and the United States. Lexaria believes that the U.S. patent could be of particular importance as it relates to the company’s pursuit of utilizing DehydraTECH-CBD in relation to its hypertension studies and its FDA Investigational New Drug application.

Phase 1b of Lexaria’s HYPER-H23-1 clinical trial, Phase 1b Randomized, Double-Blind, Placebo-Controlled Study of Safety, Pharmacokinetics, and Pharmacodynamics of DehydraTECH-CBD in Subjects with Stage 1 or Stage 2 Hypertension, is expected to begin dosing as early as October 2023, after the filing of the IND with the FDA which is expected in this summer. The five previous (non-FDA regulated) human trials of DehydraTECH-CBD have shown potential to have pronounced clinical benefits relative to anti-hypertensive therapeutics.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

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• Lexaria recently reported that dosing of the targeted 36 volunteers in its human clinical oral nicotine study, NIC-H22-1, had been completed
• The company hopes to demonstrate that its DehydraTECH(TM)-processed nicotine absorbs more quickly and more efficiently into the human bloodstream than leading oral nicotine brands
• Through previous animal testing, Lexaria showed that DehydraTECH-nicotine was up to 10x to 20x faster in delivering comparable levels of nicotine and delivered up to 6-fold higher levels of nicotine into blood plasma than concentration-matched controls
• If the findings from the human study replicate a similarly improved performance, Lexaria believes this could facilitate a more satisfying oral nicotine experience than any leading brands sold around the world today
• Success could result in an important commercial relationship developing in 2023, according to CEO Chris Bunka

Lexaria Bioscience (NASDAQ), a global innovator in drug delivery platforms, recently announced that the dosing of the targeted 36 subjects in its human clinical oral nicotine study NIC-H22-1 had been completed. In the meantime, the company has already commenced sample and data analysis and expects to report the findings as soon as possible (https://cnw.fm/u4AHx).

NIC-H22-1 is a human pharmacokinetic randomized, double-blinded, cross-over study that involved 36 human volunteers that are current cigarette smokers. Each participant visited the laboratory for dosing three times over several weeks, and during each visit, only one oral nicotine pouch was administered: Lexaria’s DehydraTECH(TM)-processed purified nicotine, On!(TM) brand manufactured by Altria, or Zyn(TM) brand manufactured by Swedish Match. Dosing began in December 2022 (https://cnw.fm/8RETj).

“We hope to demonstrate that the Lexaria DehydraTECH-processed nicotine absorbs more quickly and more efficiently into the human bloodstream than the world’s leading oral nicotine brand, Zyn(TM), or America’s third leading brand, On!(TM). If we are successful, we feel this will be a major step towards adoption of our technology into a consumer product, which could result in an important commercial relationship developing in 2023,” Lexaria CEO Chris Bunka wrote in the January 2023 annual letter to stakeholders (https://cnw.fm/Ueieg).

The study results from years of work as Lexaria sought – and continues to seek – a safe alternative to vaping or cigarette smoking, methods of nicotine intake that pose significant dangers to the health of smokers. Data from the World Health Organization (“WHO”) shows that over seven million people die each year due to direct tobacco use, while about 1.2 million non-smokers die because of exposure to second-hand smoke (https://cnw.fm/knvkM). And while vapes or e-cigarettes were developed as less harmful alternatives to conventional cigarettes (“c-cigarettes”) because they do not contain combustible tobacco (https://cnw.fm/ngb7L), NIH-funded studies show that long-term use of e-cigarettes or vaping products can significantly affect the function of blood vessels, increasing the risk of cardiovascular disease (https://cnw.fm/L6kvS).

Over the years, oral nicotine pouches entered the market as companies sought to reduce the societal impact of tobacco globally, and their uptake has been on the up since. According to a 2023 report, the global nicotine pouches market is projected to grow from $4.69 billion in 2022 to $11.91 billion in 2029, representing a CAGR of 13.4% (https://cnw.fm/3QA0d). But despite this projected growth, nicotine pouches have been shown to deliver lower nicotine levels to the blood than with cigarettes, with the time taken to reach peak levels being slower too (https://cnw.fm/xpQVd).

A reluctance by industry to embrace modern technology – has contributed to the failure of older, slow-acting traditional nicotine products to woo smokers; especially considering that in 2020, cigarettes accounted for 84.1% of the retail value sales of all nicotine products, down from 88.9% in 2017 (https://cnw.fm/O3AjX). Given that the global nicotine market is worth roughly $1 Trillion per year, each percentage point of sales represents about $10 billion in revenue. However, Lexaria believes its fast-acting technology – which decreases wait times from as long as an hour to just 3-6 minutes in animal testing – points to a possible seismic shift if improved DehydraTECH nicotine pouches hit the market.

Through animal testing, Lexaria showed that DehydraTECH-nicotine was up to 10x to 20x faster in delivering comparable levels of nicotine into the bloodstream than the peak of concentration-matched controls. The technology also went on to far exceed their total delivery; in particular, it delivered up to 6-fold higher nicotine levels into blood plasma (https://cnw.fm/lknLU). If the findings from the human study replicate similarly improved performance, Lexaria believes this could facilitate a more satisfying oral nicotine experience than any leading brands sold around the world today.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

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• Lexaria’s patented DehydraTECH(TM) technology enhances drug bioavailability, making it useful for a wide range of product formats, including pharmaceuticals, neutraceuticals, consumer packaged goods, and over-the-counter pills, capsules, tablets, and oral suspensions
• The company is currently exploring the potential benefits of DehydraTECH related to several molecules including, purified nicotine, CBD, antiviral drugs, human hormones, and PDE5 inhibitors
• Lexaria recently announced the completion of its diabetes animal study DIAB-A22-1 with at least three positive outcomes using DehydraTECH-CBD
• California-based InClin, Inc. has been awarded the contract for clinical research organization services for the expected upcoming FDA-registered, U.S. Phase 1b IND hypertension study, HYPER-H23-1
• Four new patents have been added to Lexaria’s portfolio, bringing the total to 32 granted patents and more pending worldwide

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, is improving how active pharmaceutical ingredients (“APIs”) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules through its patented DehydraTECH(TM) technology. DehydraTECH can be used with a wide range of product formats, including pharmaceuticals, neutraceuticals, consumer packaged goods, and over-the-counter pills, capsules, tablets, and oral suspensions.

Lexaria is focusing its ongoing research and development efforts on advancing product candidates across several key segments, including nicotine replacement, cannabidiol (“CBD”) for hypertension, diabetes and epilepsy, antivirals, human hormones, and phosphodiesterase type 5 (“PDE5”) inhibitors.

The company recently announced the completion of its diabetes animal study DIAB-A22-1, with at least three positive outcomes, including weight loss in obese diabetic-conditioned animals, with improved triglycerides and cholesterol levels. Lexaria plans to conduct additional investigations to learn what an optimum DehydraTECH-CBD dose related to both weight loss and increased physical activity might be, considering that the higher dose studied may have created sedative-like effects of CBD triggering hypolocomotion, which has been observed upon high systemic exposure (https://cnw.fm/B2IOI).

Separately, Lexaria has also announced that California-based InClin, Inc. has been awarded the contract for clinical research organization (“CRO”) services for the expected upcoming Food and Drug Administration (“FDA”)-registered, U.S. Phase 1b Investigational New Drug (“IND”) hypertension study HYPER-H23-1 with its DehydraTECH-CBD.

The study is entitled ‘A Phase 1b Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Pharmacokinetics, and Pharmacodynamics of DehydraTECH-CBD in Subjects with Stage 1 or Stage 2 Hypertension’. The primary objective of this study will be to evaluate the safety and tolerability in up to 120 hypertensive patients, with secondary objectives of efficacy evaluation in reducing blood pressure and detailed pharmacokinetic testing.

InClin is preparing for the study start-up, and Lexaria is expected to begin with patient dosing as soon as possible after the FDA IND filing and review are complete. The company anticipates filing the IND this summer, with FDA authorization likely to follow within about 60 days – resulting in Phase 1b trial commencement of patient dosing as early as October 2023.

According to a recent press release, InClin’s study start-up services include, but are not limited to, clinical site evaluation and selection, personnel and site training, project management, clinical database design and management, quality assurance support, medical writing, study documentation creation, biostatistics and programming, support vendor coordination, Independent Review Board submissions and more (https://cnw.fm/tnB9F).

At the end of April, Lexaria announced that it had received notification of being awarded or allowed four new patents, bringing the total up to 32 granted or allowed patents and even more pending worldwide. The new patents include the United States, Japan, Australia, and Canada. The patent in the U.S. will be the first for Patent Family #21: Compositions and Methods of Treating Hypertension, which the company believes will be particularly important related to its pursuit of utilizing DehydraTECH-CBD concerning the company’s upcoming FDA IND application (https://cnw.fm/lJnXx).

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

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• Lexaria just awarded InClin, Inc. the contract for CRO services, in a move that lines up with the company’s upcoming FDA-registered, U.S. Phase 1b IND hypertension study, HYPER-H23-1
• InClin will manage the study in the form of clinical site evaluation and selection, project management, personnel, site training, and more
• Patient dosing is set to kick off as soon as possible once the expected FDA IND filing and review is completed, which Lexaria hopes will be done this summer
• HYPER-H23-1 will be Lexaria’s most ambitious study yet, and upon its completion, it will move the company closer to FDA approval of its patented DehydraTECH(TM)-processed CBD

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, just announced the awarding of the contract for clinical research organization (“CRO”) services to California-based InClin, Inc. This move is in line with the company’s upcoming Food and Drug Administration (“FDA”)-registered, U.S. Phase 1b Investigational New Drug (“IND”) hypertension study, HYPER-H23-1 that will explore the potential of its patented DehydraTECH(TM)-processed cannabidiol (“DehydraTECH-CBD”) for the treatment of hypertension (https://cnw.fm/8WGqS).

The study will build on five previous Lexaria studies dating back to 2018, which were each successful, evidencing significant reductions in resting blood pressure over acute and multi-week dosing regimens on 134 healthy and hypertensive persons. The studies also showed that DehydraTECH-CBD produced zero serious adverse events, highlighting its potential to have pronounced clinical benefits relative to available anti-hypertensive therapeutics. The uniqueness of this product is further evidenced by its superior ability to reduce blood pressure over other oral CBD formulations currently in the market.

InClin will help with the study in the form of clinical site evaluation and selection, project management, personnel, site training, clinical database design and management, and quality assurance support. It will also be responsible for medical writing, study documentation creation, biostatistics and programming, support vendor coordination, Independent Review Board (“IRB”) submissions, and more. Study start-up is about to begin, with patient dosing set to kick off as soon as the expected FDA IND filing and review is completed, which Lexaria hopes will be done this summer. Upon the filing, Lexaria hopes for FDA authorization within about 60 days, after which the Phase 1(b) trial aggressively targeting the commencement of patient dosing will kick off.

HYPER-H23-1, titled “A Phase 1b Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Pharmacokinetics, and Pharmacodynamics of DehydraTECH-CBD in Subjects with Stage 1 or Stage 2 Hypertension,” will be Lexaria’s most ambitious study yet. Its primary objective will be to evaluate safety and tolerability in up to 120 hypertensive patients, with secondary objectives including efficacy evaluation in reducing blood pressure together with detailed pharmacokinetic testing. Its successful completion will inch Lexaria closer to FDA approval of its DehydraTECH-CBD. But, more importantly, it will stamp Lexaria’s position as a leader in its space, having come up with a product that achieves a sustained decrease in resting blood pressure following multiple weeks of oral CBD dosing.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

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Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug-delivery platforms, has completed dosing for 36 subjects in its human clinical oral nicotine study: NIC-H22-1. According to the announcement, the study is the result of the focus Lexaria has had for years on oral nicotine formulations as an alternative to vaping or smoking; the company noted that results from the study could lead to more rapid commercial adoption and distribution of its patented DehydraTECH(TM) absorption technology, which is designed to improve oral uptake. Statistics show that some 7 million people die every year from cigarette smoking, and alternatives for nicotine delivery are desperately needed. Lexaria’s DehydraTECH-nicotine is already patent granted for oral nicotine delivery in Australia and pending in numerous other countries. The company noted that its DehydraTECH-powered purified nicotine white pouch formulation contains no tobacco, and studies show that its DehydraTECH-nicotine can be 10 to 20 times fast and deliver up to tenfold higher levels of nicotine into blood plasma from oral absorption than concentration-matched controls. LEXX’s NIC-H22-1 study is a human pharmacokinetic randomized, double-blinded, cross-over study with a minimum of 36 human volunteers who currently smoke cigarettes. The study objectives include determining the quantity of nicotine in blood at various time points and collecting vital-sign data, such as blood pressure, heart rate and respiratory rate; Lexaria will provide further updates and any relevant material findings as they become available.

To view the full press release, visit https://cnw.fm/OnTm3

About Lexaria Bioscience Corp.

Lexaria Bioscience’s patented drug-delivery technology, DehydraTECH(TM), improves the way active pharmaceutical ingredients (“APIs”) enter the bloodstream through oral delivery. Since 2016, DehydraTECH has repeatedly demonstrated the ability to increase bioabsorption with cannabinoids, antiviral drugs, PDE5 inhibitors and more. DehydraTECH has also evidenced an ability to deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 28 patents granted and many patents pending worldwide. For more information about the company, please visit www.LexariaBioscience.com. 

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

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• Lexaria has received notifications of four new patents either awarded or allowed
• After the awarding of these patents, Lexaria’s total patent portfolio will have grown to 32 granted patents worldwide
• The new granted patent in Japan is under Patent Family #3: Stable Ready-to-Drink Beverage Compositions Comprising Lipophilic Active Agents
• The new granted Australian patent is under Patent Family #18: Compositions and Methods for Enhanced Delivery of Antiviral Agents
• The new allowed Canadian patent is under Patent Family #8: Compositions Infused with Nicotine Compounds and Methods of Use Thereof
• The new allowed US patent is under Patent Family #21: Compositions and Methods for Treating Hypertension and is the first patent in the Patent Family

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms and the global leader in enhancing the speed and efficiency of orally-delivered fat-soluble active molecules and drugs through its patented DehydraTECH(TM) technology – has announced that the company has received notification of four newly awarded or allowed patents (https://cnw.fm/EDyAd). The new patents will add to Lexaria’s growing portfolio, bringing the total number of patents granted worldwide to 32, with several more pending.

Lexaria’s newly awarded or allowed patents include the following:

• Japan: Lexaria’s new patent in Japan is under Patent Family #3: Stable Ready-to-Drink Beverage Compositions Comprising Lipophilic Active Agents. This patent is the fifth awarded in Japan, strengthening the company’s growing Japanese patent portfolio. Under this particular patent family, Lexaria has existing patents in Australia, India, Japan, and Mexico.
• Australia: Lexaria’s new Australian patent is categorized under Patent Family #18: Compositions and Methods for Enhanced Delivery of Antiviral Agents. The new patent brings Lexaria’s total in Australia to ten and is the second patent in this Patent Family, following a similar patent in the United States awarded in 2022.
• Canada: Lexaria’s Canadian patent under Patent Family #8: Compositions Infused with Nicotine Compounds and Methods of Use Thereof has been allowed. This will be Lexaria’s second patent in this Patent Family and follows a similar issuance in Australia in 2022.
• United States: Lexaria has been notified that a new patent under Patent Family #21: Compositions and Methods for Treating Hypertension has been allowed in the US. The company believes this patent could provide significant importance in its pursuit of utilizing DehydraTECH-CBD concerning its expected upcoming FDA Investigational New Drug application. The outcomes of a series of hypertension studies already completed were instrumental in achieving this particular patent and is the first patent in the Patent Family.

When a patent is “allowed,” it means that the patent office has notified the company that it has been determined that they will soon grant the patent, often subject to some administrative tasks and/or fees.

Lexaria’s DehydraTECH technology speeds up delivery, increases bioavailability, increases brain absorption, improves drug potency, reduces drug administration cost, and masks unwanted taste. The company has conducted animal studies that demonstrated a propensity for DehydraTECH to elevate the quantity of drug delivered across the blood-brain barrier by as much as 1,700 percent, initiating additional new patent applications and opening possibilities for improved drug delivery.

Two markets of penetration for Lexaria include cardiovascular drugs and CBD. The global cardiovascular drug market is expected to reach $173.48 billion by 2026 (https://cnw.fm/HTuz0). The global CBD market is expected to reach $111.8 billion by 2030 (https://cnw.fm/CJlRS). Lexaria’s DehydraTECH technology anticipates leveraging both markets and others, including oral nicotine, PDE5 inhibitors, and more avenues in which Lexaria has filed for patent protection for.

The new patents will allow Lexaria to continue its research and use of DehydraTECH for several indications. The patents offer protection on the company’s technology and allow it to explore further additional opportunities for use – reducing drug administration costs, enhancing efficacy, and more.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

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• Zacks recently released a research report covering Lexaria Bioscience, a global innovator in drug delivery platforms
• The report discusses the company’s ongoing research and development (“R&D”) programs, forecasting penetration into global markets for hypertension, oral nicotine delivery, and antiviral product categories
• Lexaria is targeting conditions with significant market potential, including hypertension, diabetes, dementia, and seizures
• These programs position the company for entry into collaborative opportunities to support further growth and provide growth capital

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, featured in a recently released research report from Zacks Small-Cap Research (“SCR”) (https://cnw.fm/R891E). The report considers the potential approval and commercialization of products processed with the company’s patented DehydraTECH(TM) drug delivery platform technology that increases drug bioavailability, and ongoing research and development (“R&D”) activities, including recent revelations that the platform technology may offer a new mechanism of action, to support a $14.00 share valuation (https://cnw.fm/e2bXG).

“DehydraTECH offers several attractive features: substantial improvement in bioabsorption in terms of time to measurable plasma levels and AUC (area under the curve), brain permeation, taste masking, and side effect reduction. As DehydraTECH does not employ a covalent bond, [it] is not a new molecular entity and can rely on previously conducted safety and efficacy data to obtain regulatory approval,” the report reads.

The report highlights the company’s accomplishments during the current financial year 2023, which began September 1, 2022, acknowledging the considerable ground Lexaria has traversed with its research and development (“R&D”) activities. For example, the lead R&D program seeks to investigate DehydraTECH-processed cannabidiol (“CBD”) for the treatment of hypertension; five human clinical trials have been conducted to date, yielding positive results.

These results come amid increasing interest from big pharma. In early 2023, for instance, AstraZeneca (NASDAQ: AZN) initiated a bid to acquire CinCor Pharma, Inc., a US-based clinical-stage biopharmaceutical company developing novel treatment for resistant and uncontrolled hypertension as well as chronic kidney disease. Though the bid is yet to be accepted, according to a disclaimer on AstraZeneca’s website (https://cnw.fm/jpQAW), the juggernaut’s interest, Zacks’ report explains, “accentuates the unmet need for effective control of hypertension and provides a healthy backdrop for further work by Lexaria in this area.”

This additional work comes in the form of an expected Food and Drug Administration (“FDA”)-approved Phase 1b clinical study. Accordingly, Lexaria intends to submit its Investigational New Drug (“IND”) application for the hypertension program mid-year, with the study expected to commence in the second half of the year, according to the report.

In addition, Lexaria’s efficient use of capital has allowed it to expand its R&D into new preclinical work, including efforts evaluating DehydraTECH-CBD as a potential treatment for diabetes, dementia, and seizures. And as is synonymous with all its R&D programs, these efforts are not only strategic but also influenced by an ever-present market need.

The company took an interest in the seizure space following the FDA’s approval of GW Pharmaceuticals’ Epidiolex, acquired by Jazz Pharmaceuticals, a CBD oral solution for the treatment of seizures in children with Lennox-Gastaut or Dravet syndrome. This marked the first time a drug containing an active ingredient from the cannabis plant had received approval. With regulatory approval in the bag, Epidiolex would go on to generate $750 million in revenues in 2022, a figure that will likely increase to over $1 billion by 2024. This success spurred Lexaria to perform its own studies evaluating the efficacy of DehydraTECH-CBD for seizures. In results released in November last year, the company established that DehydraTECH-CBD worked faster and better at lower doses than Epidiolex (https://cnw.fm/V9cp1).

Regarding dementia, the report underlines that although there are several approved drugs, they have had limited benefits, lacked the clear-cut benefit desired, or resulted in adverse side effects. “This leaves the dementia field wide open for therapies that can either slow or improve the symptoms of dementia,” the report continues. For its part, Lexaria intends to capitalize on this gap and has initiated a study evaluating the potential therapeutic use of DehydraTECH-CBD in dementia.

The company is also evaluating other DehydraTECH-processed candidates, including oral nicotine, antivirals, PDE5 inhibitors, hormones, and more. Of these focus areas, the report projects penetration into global markets for hypertension, oral nicotine delivery, and antiviral product categories.

“While still early stage, these programs could be excellent partnership opportunities that will support further growth and potentially provide growth capital,” the report concludes.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

To receive instant SMS alerts, text CANNABIS to 21000 (U.S. Mobile Phones Only)

For more information please visit https://www.cannabisnewswire.com

Please see full terms of use and disclaimers on the CannabisNewsWire website applicable to all content provided by CNW, wherever published or re-published: http://CNW.fm/Disclaimer

Do you have questions or are you interested in working with CNW? Ask our Editor

CannabisNewsWire (CNW)
Denver, Colorado
www.cannabisnewswire.com
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Editor@CannabisNewsWire.com

CannabisNewsWire is part of the InvestorBrandNetwork.