A group of Italian researchers has discovered that the use of a marijuana extract daily decreased pain and other symptoms brought about by burning mouth syndrome. The study’s results were published in the journal October issue of “Pain Medicine” journal.
Burning mouth syndrome is defined by the International Headache Society as an abnormal or burning sensation, which recurs daily for more than two hours every day for more than a three-month period. While its origin remains unknown, the condition can affect the sides of cheeks, lips, and tongue as well as the roof of the mouth.
To carry out the study, scientists in Turin enlisted 17 patients who had been diagnosed with burning mouth syndrome and treated them using a full-plant marijuana extract every day over a four-week period. Every dose that was administered was made up of 1 gram of the pharmaceutical cannabis extract that had been diluted with 10 g of olive oil.
The authors reported that until now, no studies had given evidence of a safe and reliable treatment for the management of burning mouth syndrome for the long term, both in terms of quality of life and symptom relief. Their study was the first that examined the role of cannabinoids in managing unresponsive burning mouth syndrome. The background and rationale of the study on the medicinal attributes of marijuana were reported in an international directory of research studies. The listing of the study states that hemp or cannabis sativa and its components, particularly cannabinoids, have been the center of a considerable amount of research.
The researchers observed the intensity of pain in their study participants to measure the effectiveness of the marijuana extract. They evaluated this using four different clinical measurements. Levels of depression and anxiety were also considered, in addition to any unexpected or adverse effects reported by the participants of the study. Additionally, pain intensity was evaluated both before the study, after the marijuana extract had been given to the patients and during the six-month period after the protocol was administered.
The study’s findings state that the participants exhibited steady significant improvement with regard to the remission of the condition’s symptoms. A favorable improvement in the levels of depression and anxiety was also recorded. Furthermore, no patient had to stop the treatment because of adverse events.
The authors of the study therefore concluded that the treatment was not only safe but also effective and called for bigger and controlled trials with placebo control or different therapeutic approaches to be done.
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